e-ISSN 2329-0072


Published: 2016-07-11

Clinical Therapeutic Effect of Sheet Split-Thickness Skin Graft with Micropores in Repairing Third-Degree Burn Wounds on the Hands

Xiaopeng Zheng, Tiansheng Chen, Lisen Zhang, Ruibin Cheng, Fei Chang, Shizhao Ji, Yu Sun, Xiaoyan Hu, Shichu Xiao, Zhaofan Xia

(Burn and Trauma Center, Changhai Hospital, Second Military Medical University, Shanghai, China (mainland))

Med Sci Tech 2016; 57:74-80

DOI: 10.12659/MST.900085

BACKGROUND: Sheet split-thickness skin grafting is the main method used to repair the third-degree burn wounds on the hands. However, because of the poor drainage of sheet skin, there is often subcutaneous effusion after sheet grafting, which can form hematomas and seromas, leading to partial necrosis of the grafted skin, and critically affect the appearance and function of the hand. Thus, there is urgent need to find a more stable method to improve the survival rate of the grafted skin.
MATERIAL AND METHODS: Sixty-two cases with third-degree hand burns were collected from 2010 to 2014 in the Burn and Trauma Center of Changhai Hospital in Shanghai and in the Burns Department of the 100th Hospital of the PLA in Suzhou city. According to the methods of skin grafts, the cases were divided into treatment group (sheet split-thickness skin graft with micropores) and control group (sheet split-thickness skin graft without micropores). Subcutaneous hematomas and seromas were observed, and the rate of graft loss was calculated. All cases were followed up for 1 year to assess the scar formation. Animal experiments were performed to observe the changes of the micropore size and the collagen arrangement at the micropore region after sheet split-thickness skin graft with micropores.
RESULTS: There were 32 cases were in the treatment group and 30 in the control group. One week after the operation, the incidence of subcutaneous hemorrhages and seromas in the treatment group (46.9%) was significantly lower than in the control group (73.3%), and the difference has statistical significance (P<0.05). Compared with that of the c... read more

Keywords: Burns, Cicatrix, hand injuries, Micropore Filters, Skin Transplantation

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