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Medical Science Technology is an open access, peer-reviewed journal that is dedicated to publishing research in all areas of applied technology in medicine and biomedical research. It is aimed at readers and authors with their main interest in the application of technology to solve problems in the medical and biological sciences, and overlapping areas of medicine and technology, such as (but not limited... read more


Published: 2016-10-28

Treatment of Depression in Patients with Diabetes Mellitus: A Review

Katarzyna Pietrzyk-Orkisz, Katarzyna Józefacka-Majewska, Marlena Zajączkowska, Piotr Gałecki

(Department of Adult Psychiatry, Medical University of Łódź, Łódź, Poland)

Med Sci Tech 2016; 57:110-115

DOI: 10.12659/MST.900780


ABSTRACT: Depression and diabetes mellitus are increasingly recognized as comorbid chronic diseases. The relationship between diabetes and depression, argued to be bidirectional, depends on many factors and can be explained by behavior and physiology. Comorbid depression with diabetes increases the risk of developing diabetes-related complications, which in turn exacerbates the course of depression and imposes a huge burden on healthcare costs. Thus, treatment of comorbid depression is vital for the clinical care of patients with diabetes. It has been argued that antidepressants are effective in the treatment of depression in diabetic patients. Treatment with antidepressant medications can directly affect blood glucose levels: SSRIs and MAOIs improve glycemic control, whereas TCAs and (probably) SNRIs cause adverse effects. The effects of other new antidepressants on glycemic control should be confirmed, and results thus far are promising. In patients with diabetic neuropathic pain, TCAs and SNRIs are useful. Treatment of depression improves health-related behaviors and glycemic control, which are fundamental to the management of diabetes and prevention or delay of long-term complications.

Keywords: Antidepressive Agents, Comorbidity, Depression, Diabetes Mellitus




Published: 2016-10-12

Comparison of Attitudes of Young Citizens of the Czech Republic, Poland, and Slovakia Towards Liberalizat...


Andrzej Brodziak, Pavel Grabczak, Jana Kutnohorska, Alicja Różyk-Myrta

Med Sci Tech 2016; 57:104-109

DOI: 10.12659/MST.900785

Published: 2016-09-26

The Role of Dvl3 in the Context of Neurodevelopmental Processes and Neuropsychiatric Disorders


Marlena Zajączkowska, Monika Talarowska, Katarzyna Pietrzyk-Orkisz, Piotr Gałecki

Med Sci Tech 2016; 57:95-103

DOI: 10.12659/MST.900492