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In-stent restenosis treatment – our own experience Part I. Clinical restenosis risk factors

Beata Mikulska, Krzysztof Andrysiewicz, Elżbieta Cieplucha, Krzysztof Chiżyński

Med Sci Tech 2008; 49(3): RA155-158

ID: 881613

Available online:

Published: 2008-03-21


Introduction: The purpose of this study was to evaluate the clinical restenosis risk factors in the patients after bare metal stent (BMS) implantation. Materials and methods: The examination comprised 98 consecutive patients with in-stent restenosis (ISR). The study group consists of 59 patients, aged 37-87 (mean age 60.6) with ISR after BMS implantation treated with the aid of DES implantation and the control group consists of 39 patients, aged 40-80 (mean age 60) with ISR after BMS implantation treated with plain optimal balloon angioplasty (POBA). Clinical and laboratory risks factors of ISR such as: age, gender, DM occurrence, hypertension, lipid disturbances, smoking after PCI, coronary instability were analyzed. Results: There was 64.1% males in the study group vs. 56.4% males in the control group. The study group patients did not differ from the control group patients in the frequency of smoking: current (20.3 vs. 17.9%) or past (up to 5 years ago) (45.8 vs. 46.1%). In the study group diabetes (49.1 vs. 25.6%; p=0.020) and hypertension (83 vs. 61.5%); p=0.017) occurred essentially more often. BMI was also higher (27.9 vs. 26.1 kg/m2; p=0.028). In 59% of patients in the control group and 74.3% of patients in the study group BMS was implanted in ACS (NS). Conclusions: 1. Atherosclerosis risk factors such as especially diabetes and hypertension was connected with in bare metal stent restenosis. 2. In bare metal stent restenosis was observed most often in patients who underwent stent implantation in an acute coronary syndrome. (Clin Exp Med Lett 2008; 49(3): 155-158)

Keywords: in-stent restenosis, bare metal stent, restenosis risk factors, acute coronary syndrome



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