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Introduction: The most of malignant skin tumours belong to one of the two groups: non-melanoma skin cancer (NMSC), which is the most prevalent one, and melanoma. The incidence of cancer in population with renal transplant is 100 times higher than in age-matched individuals from the general population ranging from 4% to 18% (mean 6%). Compared with the general population, the overall incidence among renal transplant recipients is 250 times higher for squamous cell carcinoma, and 10 times higher for basal cell carcinoma, being one of the most common complications of organ transplantation. Case report: This case presents a patient using immunosuppressive and steroid therapy for seven years after renal transplantation, who developed disseminated NMSC - squamous cell carcinoma (SCC).”Chemotherapy and radiotherapy did not stop the progress of disease. The patient died after 2 years due to disseminated neoplastic disease. (Clin Exp Med Lett 2009; 50(2):119-120)

Keywords: renal transplant, squamous cell carcinoma, disseminated neoplasm, immunosuppressive therapy, non melanoma skin cancer, family physician