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Sevoflurane allows for decreasing the total dose of muscle relaxant for laparoscopic gastric banding

Tomasz M Gaszyński, Waldemar Machała, Tomasz B Szewczyk, Wojciech P Gaszyński

Med Sci Tech 2007; 48(1): RA41-43

ID: 881534

Available online:

Published: 1999-11-30


Introduction: Laparoscopic procedures require adequate relaxation which is usually achieved by additional doses of muscle relaxants. However, from clinical experience we see that increasing in Vol% of volatile anesthetics may increase synergic effect on neuromuscular junction causing reduction in total dose of relaxants.The aim of the study was to investigate influence of sevoflurane on requirement for additional dose of relaxant and operation conditions during laparoscopic gastric banding (LAGB) procedures. Material and Methods: 43 morbidly obese patients scheduled for LAGB were randomly allocated into two groups: A- intubation dose of 0,6 mg/kg of atracurium and additional dose 0,2 mg/kg when TOF reached 2 responses (20 pts), B- only intubation dose (23 pts). Anesthesia was conducted with sevoflurane/oxygen/N2O/fentanyl. Operation conditions was estimated during surgery by surgeon. Results: Demographic data, duration of procedure, time to safe extubation did not differ between groups. In 3 cases (13%) in group B deterioration in operation conditions was observed. Conclusions: A single dose of relaxant during sevoflurane volatile general anesthesia in most cases provides efficient paralysis during procedure. LGB – Laparoscopic Gastric Banding; TBW - Total Body Weight; CW – Corrected Weight; IBW – Ideal Body Weight. (Clin Exp Med Lett 2007; 48(1):41-43)

Keywords: morbid obesity, Laparoscopy, muscle relaxants, sevoflurane, volatileanesthesia



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