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AmJCaseRep

High Prevalence of Thyroid Disorders in Pregnant Women in A Region of Eastern Turkey

Nurinnisa Ozturk, Nurcan Kilic Baygutalp, Canan Yigit, Harun Polat, Ebubekir Bakan, Mehmet Ali Gul, Nuri Bakan

Med Sci Tech 2016; 57:21-24

DOI: 10.12659/MST.896956

Available online: 2016-02-04

Published: 2016-02-04


BACKGROUND: In this study, we aimed to determine the prevalence of thyroid dysfunction in pregnant women in our region.
MATERIAL AND METHODS: The study included 1580 women in the first trimester of pregnancy. Serum thyroid stimulating hormone, free triiodothyronine, and free thyroxine levels were measured. The reference intervals for thyroid stimulating hormone, free triiodothyronine, and free thyroxine were 0.35–4.97 mIU/L, 1.71–3.71 pg/ml, and 0.7–1.48 ng/dl, respectively. Mean ± standard deviation values were calculated for the measured analytes.
RESULTS: When the results were grouped according to the reference ranges of analytes, subclinical hyperthyroidism was observed in 70/1580 (4.43%), and subclinical hypothyroidism was observed in 32/1580 (2.02%).
CONCLUSIONS: Thyroid dysfunction prevalence of pregnant women in our region was about 9%, which is high. Considering that subclinical thyroid dysfunction has early and late complications, screening of all pregnant women in the first trimester for thyroid diseases should be considered by clinicians in order to prevent obstetrical adverse outcomes and neurological damage in children.

Keywords: hyperthyroidism, Hypothyroidism, Pregnancy Trimester, First



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