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Ludwina Szczepaniak-Chicheł, Piotr Bręborowicz, Marcin Grabicki, Tatiana Mularek-Kubzdela, Magdalena Janus, Elżbieta Bręborowicz, Aleksander Araszkiewicz, Katarzyna Kolasińska–Malkowska, Anna Olasińska, Maciej Lesiak, Stefan Grajek, Andrzej Cieśliński
Med Sci Tech 2005; 46(3): RA51-55
ID: 881465
Background. Coronary risk factors modification is a basic aim for both primary and secondary prevention of the is chemic heart disease. The aim of this studywas to assess the prevalence of main coronary risk in patients with a cute coronary syndrome. Materials and methods. 1082 consecutive patients (762 men and 320 women; mean age 61,5±11,4 years) admitted between 15.10.2001 and 01.02.2003 with diagnosis of acute coronary syndrome were analyzed. Diagnosis of acute coronary syndrome was made according to the typical clinical symptoms, ischemic ECG changes, elevation of myocardial necrosis markers and coronary angiography. The prevalence of following risk factors according to age (<50; between 50 and 65; and >65) and gender was estimated: smoking, arterial hypertension, diabetes mellitus, hyperlipidaemia and family history of CHD. Chi-square test was used in statistical analysis. Results. The prevalence of the particular risk factors in the investigated population was: arterial hypertension- 66,9% ( women – 77,2%, men – 62,6%; p<0,00001); diabetes mellitus – 18,2% (women – 23,8%, men – 15,6%; p=0,001); hyperlipidaemia – 61,2% (women – 61,6%, men – 62,6%; ns); family history of IHD – 44,3% (women – 48,4%, men – 42,5%; p=0,001); smoking – 65,5% (women – 45,9%, men – 73,8%; p<0,00001). On average there were 3,2 risk factors per patient. Conclusions. High prevalence of investigated risk factors confirms the irsessential role in the pathogenesis and course of ischaemic heart disease. Sex and age related differences in risk factors profile reflect biological and behavioral variations and aging. High incidence of modifiable risk factors in this population shows necessity for education on life style modification and treatment.(Clin. Exp. Med. Lett. 2005; 46(3):51-55)
Keywords: coronary risk factors, acute coronary syndrome, hyperlipidaemia, arterial hypertension, Diabetes Mellitus