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The results of surgical treatment of advanced liver tumors

Adam Durczyński, Piotr Hogendorf, Dariusz Szymański, Jarosław Hołyński, Piotr Grzelak, Grażyna Poznańska, Janusz Strzelczyk

Med Sci Tech 2011; 52(1-2): RA63-65

ID: 882078

Background:    Since they have a largely asymptomatic natural course, liver tumors are usually diagnosed in the late stage of advancement. We present our experience with surgical treatment of advanced liver tumors.
    Material/Methods:    The aim of this study was to retrospectively analyze our experiences with patients with advanced, solitary liver tumors treated in our center in 2009, with right or left hemihepatectomy. Age, sex, BMI, type, size and localization of tumor, comorbidities, delay time between diagnosis and surgery, time of hospitalization, type of operation, intra- and postoperative complications, amount of transfused packed red blood cells (PRBCs) and fresh frozen plasma (FFP) were analyzed retrospectively.
    Results:    The study group consisted of 30 patients (57% males, 43% females); the average age was 58 years and BMI 26.5 kg/m2. Comorbidities were found in 14 patients. In 20 patients the tumor was localized in right and in 10 in the left hepatic lobe, and appropriate hemihepatectomies were performed. In 22 patients malignant neoplasm was diagnosed (13 cases of colorectal cancer metastasis and 9 cases of hepatocellular cancer); 8 patients had benign tumors (5 cases of adenoma and 3 cases of hemangioma). The mean tumor volume was 110 cm3. The mean delay time between diagnosis and surgery was 36 days, and duration of hospitalization was 10 days. There were 10 postoperative complications and no intraoperative complications. Most patients did not require PRBCs and FFP transfusion.
    Conclusions:    The dynamic development of liver surgery has enabled radicalization of operations in advanced solitary liver tumors, with minimal intraoperative blood loss, low perioperative mortality and short hospitalization period.

Keywords: major liver resection, hemihepatectomy, advanced solitary liver tumors

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